Trademarks: Abilitat; Abilify; Aripiprex
Molecular Formula: C23H27Cl2N3O2
CAS Registry Number: 129722-12-9
CAS Name: 7-{4-[4-(2,3-dichlorophenyl)piperazin-1-yl]butoxy}-1,2,3,4-tetrahydroquinolin-2-one
Molecular Weight: 448.385
SMILES: ClC1=CC=CC(N2CCN(CCCCOC3=CC4=C(CCC(=O)N4)C=C3)CC2)=C1Cl
InChI Key: CEUORZQYGODEFX-UHFFFAOYSA-N
InChI: InChI=1S/C23H27Cl2N3O2/c24-19-4-3-5-21(23(19)25)28-13-11-27(12-14-28)10-1-2-15-30-18-8-6-17-7-9-22(29)26-20(17)16-18/h3-6,8,16H,1-2,7,9-15H2,(H,26,29)
Activity: Antipsychotic Agents; Treatment of Schizophrenia; Treatment of Bipolar Disorder; Partial Dopamine Agonist
Status: Launched 2002
Originator: Otsuka/Bristol-Myers Squibb
Aripiprazole synthesis: EP0367141B1
Aripiprazole synthesis: WO2004099152A1
1. Oshiro, Y.; et. al. Carbostyril derivatives. EP0367141B1
2. Lafreniere, J.; et. al. Process for the preparation of carbostyril derivatives, such as aripiprazole and its intermediates. WO2004099152A1
