Trademarks: Zyrtec; Reactine; Cetirizina; Cetirin; Cetzine; Cetirizin; Cezin
Molecular Formula: C21H25ClN2O3
CAS Registry Number: 83881-51-0
CAS Name: [2-[4-[(4-chlorophenyl)phenylmethyl]-1- piperazinyl]ethoxy]acetic acid
Molecular Weight: 388.89
Activity: Second-generation Antihistamines; Antihistamines; Hay Fever Treatment; Allergies Treatment; H1 receptor Antagonist; Urticaria Treatment
Certizine synthesis: US4525358A (revisited in Ref. 2)
References:
1. Baltes, E.; et. al. Antihistamines, antiallergens, antispasmodics, bronchodilators. US4525358A
2. Li, J. J. (Eds); et. al. Contemporary Drug Synthesis, 2004, Wiley Publication.
3. Curran, M. P.; et. al. Cetirizine: a review of its use in allergic disorders. Drugs 2004, 64(5), 523-561. (activity)
