Showing posts with label Cabiralizumab. Show all posts
Showing posts with label Cabiralizumab. Show all posts

Monday, October 24, 2016

Drugs in Clinical Pipeline: Cabiralizumab | Monoclonal Antibodies (mAbs) | Cancer Treatment | Anti-Inflammatory Agents | Anti-CSF1R Antibody


Cabiralizumab (also known as FPA008) is a humanized IgG4 monoclonal antibody that binds to human colony stimulating factor 1 receptor (CSF1R), and blocks the ability of IL34 and CSF1 to activate CSF1R expressed on macrophages. Cabiralizumab specifically targets macrophages and monocytes, immune cells that are activated or elevated in multiple disease settings [1, 2].