Friday, June 5, 2015

Blood Type And Risk Of Cognitive Decline: Breakthrough in Predicting Diseases Such As Alzheimer

Blood Type And Risk Of Cognitive Decline: Breakthrough in Predicting Diseases Such As Alzheimer

A study conducted by researchers at the University of Sheffield in collaboration with the IRCCS San Camillo Hospital Foundation in Venice, has revealed shows that people with an ‘O’ blood type have more grey matter in their brain, which helps to protect against diseases such as Alzheimer’s, than those with ‘A’, ‘B’ or ‘AB’ blood types.

This research put light on how blood types play a role in the development of the nervous system and may cause a higher risk of developing cognitive decline.

Methodology

Researchers made the discovery after analysing the results of 189 Magnetic Resonance Imaging (MRI) scans from healthy volunteers. The researchers calculated the volumes of grey matter within the brain and explored the differences between different blood types.

Results

1. Individuals with an ‘O’ blood type have more grey matter in the posterior proportion of the cerebellum.

2. Persons with A’, ‘B’ or ‘AB’ blood types had smaller grey matter volumes in temporal and limbic regions of the brain, including the left hippocampus, which is one of the earliest part of the brain damaged by Alzheimer’s disease.

3. As we age a reduction of grey matter volumes is normally seen in the brain, but later in life this grey matter difference between blood types will intensify as a consequence of ageing.

The authors conclude as “The findings seem to indicate that people who have an ‘O’ blood type are more protected against the diseases in which volumetric reduction is seen in temporal and mediotemporal regions of the brain like with for example Alzheimer’s disease. Considering that the biology of blood types influences the development of the nervous system. We now have to understand how and why this occurs.”

Article citation: Venneri, A.; et. al. ‘O’ blood type is associated with larger grey-matter volumes in the cerebellum. Brain Research Bulletin 2015, 116. DOI:10.1016/j.brainresbull.2015.05.005