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Saturday, September 30, 2017
Drugs in Clinical Pipeline: SUVN-502 | 5-HT6 receptor antagonist | Treatment for Alzheimer's Disease
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SUVN- 502 is a novel, potent, and selective 5-HT 6 receptor antagonist with K i of 1.71 nM and exhibited antagonist like inhibition with...
Saturday, September 23, 2017
Drugs in Clinical Pipeline: CT1812 | Abeta Oligomers Receptor Antagonist | Treatment for Alzheimer's Disease
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CT1812, works by a completely novel mechanism to stop the binding of toxic proteins that build up in the brains of Alzheimer's patient...
Friday, September 15, 2017
Drugs in Clinical Pipeline: GRC 27864 | Microsomal Prostaglandin E Synthase-1 (mPGES-1) Inhibitor | Treatment for Chronic Inflammatory Diseases
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GRC 27864 is a potent, selective, orally bioavailable inhibitor of microsomal prostaglandin E synthase-1 (mPGES-1). Prostaglandins (PGs) a...
Thursday, September 14, 2017
Drugs in Clinical Pipeline: BI 409306 | PDE9A Inhibitor | Phosphodiesterase 9A Inhibitors | Treatment for Alzheimer's Disease
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Phosphodiesterases (PDEs) in the brain have shown to play an important role in synaptic plasticity and cognitive function. Among those PDE...
Wednesday, September 13, 2017
Drugs in Clinical Pipeline: TRV734 | Treatment of Acute Severe Pain | G Protein-Biased μ-Opioid receptor
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TRV734 is novel, potent, and selective G protein-biased μ -opioid receptor ligand. TRV734 robustly engage G protein coupling with efficacy...
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